Vern D. Winston, Ph.D.
Viruses of Fish
Office: Life Sciences 425
Gale Life Sciences Bldg, Rm 422
We study IHN virus, a virus which causes major losses in fish hatcheries of Idaho. The focus is on computer modeling of the surface proteins of this virus with intent of using this information to develop antiviral vaccines.
1970, Ph.D. Microbiology, University of Nebraska, Lincoln, NE
1976-1980, Postdoctoral fellow, Structure of polyoma virus, Kansas State University, Manhattan, KS
Dr. Winston joined the ISU faculty in 1980. In the ensuing 30+ years, he has been active in teaching in the Microbiology and Cell Biology curriculum (General Microbiology and Cell Biology) at the sophomore level, and his specialty (Virology) at the senior level. Dr. Winston's research has focused on a virus that is a major pathogen of fish in Idaho (Infectious Hematopoietic Necrosis Virus). Early on, this work was directed toward understanding the immune response of trout to the virus, and how the virus spreads from one fish to another. More recently the work has been directed toward studying the evolution of the virus, using molecular phylogeny and computer modeling techniques.
BIOL 2235 General Microbiology
BIOL 4475/5575 General Virology
BIOL 4478/5578 Animal Virology Laboratory
BIOL 4494 Microbiology Senior Seminar
Groome J, Lehmann-Horn F, Fan C, Wolf M, Winston V, Merlini L, Jurkat-Rott K, (2014) NaV1.4 mutations cause hypokalemic periodic paralysis by disrupting IIIS4 movement during recovery. Brain Accepted Dec 12. 2013
Santin, A. E., Searle, A. J., Winston, V. D., Powell, M. S., Hardy, R. W., Rodnick, K. J. (2013). Glycated hemoglobin is not an accurate indicator of glycemia in rainbow trout (vol. 165, pp. 343-352). Comparative Biochemistry and Physiology A.
Groome JR, Winston V. (2013) S1-S3 counter charges in the voltage sensor module of a mammalian sodium channel regulate fast inactivation. J Gen Physiol. 2013 May;141(5):601-18. doi: 10.1085/jgp.201210935. Epub 2013 Apr 15.
A. Searle, V. Winston and G. Scalarone, "Blastomyces dermatitidis: Chitinase Homology Model, in Silico Docking, and Inhibition Assay," Open Journal of Medical Microbiology, Vol. 2 No. 1, 2012, pp. 1-7.
LaPatra SE, Evilia C, Winston V. Positively selected sites on the surface glycoprotein (G) of infectious hematopoietic necrosis virus. J Gen Virol. 2008 Mar;89(Pt 3):703-8. PMID: 18272761
Pocatello, ID 83209-8007